A spinster author named Laura Reno wars against ruthless assassins who kill two of her five brothers and threaten the lives of the remaining three. A crippled railroad tycoon and former actress need to complete a rail line to a prime location where an elaborate theatre is being built. Homesteaders like Laura Reno and her family are in the way of the woman’s plans to conquer the west and resurrect her stage career. A slick-talking gunman and his cohorts are hired to facilitate Devolle’s dream and that not only includes murdering anyone who won’t sell their land to the railroad, but doing away with the Reno boys who have been robbing Devolle trains.